Resident Evil Requiem – Lead Researcher’s Office Puzzle Box Combination Guide

Francesco De Meo
A character in 'Resident Evil Requiem' holding a flashlight, with the text 'Lead Researcher's Office Puzzle Box Combination'
Here's the Lead Researcher's Office Puzzle Box Combination in Resident

As you venture deeper into the Rhodes Hill Care Center in Resident Evil Requiem, your search for the escape items will lead you to the Lead Researcher’s Office. Inside, you’ll find another locked Puzzle Box like the one in the Chairman's Office, containing a vital progression item.

However, unlike the Chairman’s puzzle box, you cannot interact with this one straight away. You’ll need a specific item to bypass a physical lock first.

Related Story CAPCOM Drops Surprise Resident Evil Requiem Demo on Every Platform, but Your Progress Won’t Carry Over

The Puzzle Box Solution

The Corrosive

Before you can even worry about the combination, you will notice the Puzzle Box is secured by a heavy padlock. This cannot be broken by any of Grace's tools and must be dissolved using the Corrosive, which is located inside the Conference Room.

Discovering the Combination

If you want to find the solution yourself, you will need to check out the photos scattered around the office. Each one provides a piece of the puzzle's solution in the background.

The Rewards

Opening the box rewards you with two important items:

  • The Sun Quartz: This is the second of the three critical items needed to escape the Rhodes Hill Care Center.
  • Organ transport box note: a note containing the instructions on how to unlock the organ transport box found in the care center's Garage. The artificial organ stored inside is crucial to solving a later puzzle.

This concludes the guide. For more help with settings and survival strategies, visit our Resident Evil Requiem Complete Walkthrough and Guides Hub.

Guides based on a full playthrough completed in the Steam 1.0 version at Standard (Classic) difficulty. Screenshots captured from the same version.

Francesco De Meo Photo

About the author: Francesco De Meo has been covering video games and technology since 2012, starting his career at small outlets like Gamersyndrome and GeekSnack. After joining Wccftech gaming section in 2015, he quickly expanded his video gaming coverage with in-depth reporting, interviews with iconic industry figures such as Grasshopper Manufacture founder and No More Heroes creator Goichi "Suda51" Suda, Resident Evil series creator Shinji Mikami, Team NINJA's president and Nioh series director Fumihiko Yasuda, and Silent Hill creator Keiichiro Toyama, reviews and on-the-ground coverage of major industry events such as Gamescom and E3. When he's not reporting or reviewing, Francesco can be found playing the genres he loves most, spending time with his six cats, reading, writing music, playing guitar and drumming for his progressive rock band.

Follow Wccftech on Google to get more of our news coverage in your feeds.

Deal of the Day

Button