While exploring the ARK research facility in Resident Evil Requiem with Grace, you will encounter two locked safes containing vital supplies. Cracking these is essential for surviving the tougher encounters against zombies and the fearsome Lickers, especially if you are playing on Standard (Classic) difficulty, where enemies are stronger.
Table of contents
Sterilization Chamber Safe

- Combination: Right 10 - Left 90 - Right 20
- Reward: 15 Handgun Ammo, 1 Molotov Cocktail, 1 Med Injector
Monitor Control Room Safe

- Combination: Left 50 - Right 60 - Left 80
- Reward: 1 Empty Bottle, 1 Bottle of Acid, 1 Med Injector
If you have opened the three safes in the Care Center, you will also unlock the No Safe is Safe Trophy/Achievement after opening the two safes above.
This concludes the guide. For more help with settings and survival strategies, visit our Resident Evil Requiem Complete Walkthrough and Guides Hub.
Guide based on a full playthrough completed in the Steam 1.0 version at Standard (Classic) difficulty. Screenshots captured from the same version.
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