AMD's Instinct MI400 and Instinct MI500 accelerators will set the stage for an epic battle in the AI segment against NVIDIA.
AMD MI400 Series Comes In MI455X "Training/Inference" & MI430X "HPC" Variants, Instinct MI500 All Set For 2027
During its Financial Analyst Day 2025, AMD highlighted its MI400 and MI500 series AI GPU accelerators as key highlights. These two Instinct families are really important for AMD's AI strategy moving forward, and the company has reaffirmed its yearly launch cadence to strengthen its AI family against NVIDIA, which is dominating the segment right now.
Next year, AMD will launch its Instinct MI400 series AI accelerators. The new lineup will be based on the CDNA 5 architecture and offers:
- Increased HBM4 Capacity & Bandwidth
- Expanded AI Formats with Higher Throughput
- Standard-Based Rack-Scale Networking (UALoE, UAL, UEC)
The official metrics list the MI400 as a 40 PFLOP (FP4) & 20 PFLOP (FP8) product, which doubles the compute capability of the MI350 series, which is a hot product for AI data centers.
In addition to the compute capability, AMD is also going to leverage HBM4 memory for its Instinct MI400 series. The new chip will offer a 50% memory capacity uplift from 288GB HBM3e to 432GB HBM4. The HBM4 standard will offer a massive 19.6 TB/s bandwidth, more than double that of the 8 TB/s for the MI350 series. The GPU will also feature a 300 GB/s scale-out bandwidth/per GPU, so some big things are coming in the next generation of Instinct.
AMD has positioned its Instinct MI400 GPUs against NVIDIA's Vera Rubin, and the high-level comparison looks something like the following:
- 1.5x Memory Capacity vs Competition
- Same Memory Bandwidth vs Competition
- Same FP4 / FP8 FLOPs vs Competition
- Same Scale-Up Bandwidth vs Competition
- 1.5x Scale-Out Bandwidth vs Competition
For the MI400 series, there will be two products, the first one is the Instinct MI455X, which is aimed at scale AI Training & Inference workloads. The other one is MI430X, which is aimed at HPC & Sovereign AI workloads, featuring hardware-based FP64 capabilities, hybrid compute (CPU+GPU), and the same HBM4 memory as the MI455X.
In 2027, AMD will be introducing its next-gen Instinct MI500 series AI accelerators. Since AMD is shifting to an annual cadence, we are going to see updates on the datacenter and AI front at a very rapid pace, similar to what NVIDIA is doing now with a standard and an "Ultra" offering. These will be used to power the next-gen AI racks and will offer a disruptive uplift in overall performance. According to AMD, the Instinct MI500 series will offer next-gen compute, memory, and interconnect capabilities.
AMD Instinct AI Accelerators:
| Accelerator Name | AMD Instinct MI500 | AMD Instinct MI400 | AMD Instinct MI350X | AMD Instinct MI325X | AMD Instinct MI300X | AMD Instinct MI250X |
|---|---|---|---|---|---|---|
| GPU Architecture | CDNA 6 | CDNA 5 | CDNA 4 | Aqua Vanjaram (CDNA 3) | Aqua Vanjaram (CDNA 3) | Aldebaran (CDNA 2) |
| GPU Process Node | 2nm | 2nm+3nm | 3nm | 5nm+6nm | 5nm+6nm | 6nm |
| XCDs (Chiplets) | TBD | 8 (MCM) | 8 (MCM) | 8 (MCM) | 8 (MCM) | 2 (MCM) 1 (Per Die) |
| GPU Cores | TBD | TBD | 16,384 | 19,456 | 19,456 | 14,080 |
| GPU Clock Speed (Max) | TBD | TBD | 2400 MHz | 2100 MHz | 2100 MHz | 1700 MHz |
| INT8 Compute | TBD | TBD | 5200 TOPS | 2614 TOPS | 2614 TOPS | 383 TOPs |
| FP6/FP4 Matrix | TBD | 40 PFLOPs | 20 PFLOPs | N/A | N/A | N/A |
| FP8 Matrix | TBD | 20 PFLOPs | 5 PFLOPs | 2.6 PFLOPs | 2.6 PFLOPs | N/A |
| FP16 Matrix | TBD | 10 PFLOPs | 2.5 PFLOPs | 1.3 PFLOPs | 1.3 PFLOPs | 383 TFLOPs |
| FP32 Vector | TBD | TBD | 157.3 TFLOPs | 163.4 TFLOPs | 163.4 TFLOPs | 95.7 TFLOPs |
| FP64 Vector | TBD | TBD | 78.6 TFLOPs | 81.7 TFLOPs | 81.7 TFLOPs | 47.9 TFLOPs |
| VRAM | HBM4E | 432 GB HBM4 | 288 GB HBM3e | 256 GB HBM3e | 192 GB HBM3 | 128 GB HBM2e |
| Infinity Cache | TBD | TBD | 256 MB | 256 MB | 256 MB | N/A |
| Memory Clock | TBD | 19.6 TB/s | 8.0 Gbps | 5.9 Gbps | 5.2 Gbps | 3.2 Gbps |
| Memory Bus | TBD | TBD | 8192-bit | 8192-bit | 8192-bit | 8192-bit |
| Memory Bandwidth | TBD | TBD | 8 TB/s | 6.0 TB/s | 5.3 TB/s | 3.2 TB/s |
| Form Factor | TBD | TBD | OAM | OAM | OAM | OAM |
| Cooling | TBD | Passive / Liquid | Passive / Liquid | Passive Cooling | Passive Cooling | Passive Cooling |
| TDP (Max) | TBD | TBD | 1400W (355X) | 1000W | 750W | 560W |
About the author: A Software Engineer by training and a PC enthusiast by passion, Hassan Mujtaba serves as Wccftech's Senior Editor for hardware section. With years of experience in the industry, he specializes in deep-dive technical analysis of next-generation CPU and GPU architectures, motherboards, and cooling solutions. His work involves not only breaking news on upcoming technologies but also extensive hands-on reviews and benchmarking.
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