AMD All-Set To Battle NVIDIA’s AI Dominance With Instinct MI400 “MI455X & MI430X” Accelerators In 2026, MI500 Is The Next Big Leap For 2027

Nov 11, 2025 at 03:46pm EST
A presentation slide titled 'Leadership Roadmap on Annual Cadence' shows AMD Instinct MI300X, MI325X, MI350 Series, MI400 Series, and MI500 Series planned from 2023 to 2027.

AMD's Instinct MI400 and Instinct MI500 accelerators will set the stage for an epic battle in the AI segment against NVIDIA.

AMD MI400 Series Comes In MI455X "Training/Inference" & MI430X "HPC" Variants, Instinct MI500 All Set For 2027

During its Financial Analyst Day 2025, AMD highlighted its MI400 and MI500 series AI GPU accelerators as key highlights. These two Instinct families are really important for AMD's AI strategy moving forward, and the company has reaffirmed its yearly launch cadence to strengthen its AI family against NVIDIA, which is dominating the segment right now.

Related Story With the Next-Gen MI450 AI Lineup, AMD Says There Will Be ‘No Excuses, No Hesitation’ in Choosing Team Red Over NVIDIA In AI Workloads

Next year, AMD will launch its Instinct MI400 series AI accelerators. The new lineup will be based on the CDNA 5 architecture and offers:

The official metrics list the MI400 as a 40 PFLOP (FP4) & 20 PFLOP (FP8) product, which doubles the compute capability of the MI350 series, which is a hot product for AI data centers.

In addition to the compute capability, AMD is also going to leverage HBM4 memory for its Instinct MI400 series. The new chip will offer a 50% memory capacity uplift from 288GB HBM3e to 432GB HBM4. The HBM4 standard will offer a massive 19.6 TB/s bandwidth, more than double that of the 8 TB/s for the MI350 series. The GPU will also feature a 300 GB/s scale-out bandwidth/per GPU, so some big things are coming in the next generation of Instinct.

AMD has positioned its Instinct MI400 GPUs against NVIDIA's Vera Rubin, and the high-level comparison looks something like the following:

For the MI400 series, there will be two products, the first one is the Instinct MI455X, which is aimed at scale AI Training & Inference workloads. The other one is MI430X, which is aimed at HPC & Sovereign AI workloads, featuring hardware-based FP64 capabilities, hybrid compute (CPU+GPU), and the same HBM4 memory as the MI455X.

In 2027, AMD will be introducing its next-gen Instinct MI500 series AI accelerators. Since AMD is shifting to an annual cadence, we are going to see updates on the datacenter and AI front at a very rapid pace, similar to what NVIDIA is doing now with a standard and an "Ultra" offering. These will be used to power the next-gen AI racks and will offer a disruptive uplift in overall performance. According to AMD, the Instinct MI500 series will offer next-gen compute, memory, and interconnect capabilities.

AMD Instinct AI Accelerators:

Accelerator NameAMD Instinct MI500AMD Instinct MI400AMD Instinct MI350XAMD Instinct MI325XAMD Instinct MI300XAMD Instinct MI250X
GPU ArchitectureCDNA Next / UDNACDNA 5CDNA 4Aqua Vanjaram (CDNA 3)Aqua Vanjaram (CDNA 3)Aldebaran (CDNA 2)
GPU Process NodeTBDTBD3nm5nm+6nm5nm+6nm6nm
XCDs (Chiplets)TBD8 (MCM)8 (MCM)8 (MCM)8 (MCM)2 (MCM)
1 (Per Die)
GPU CoresTBDTBD16,38419,45619,45614,080
GPU Clock Speed (Max)TBDTBD2400 MHz2100 MHz2100 MHz1700 MHz
INT8 ComputeTBDTBD5200 TOPS2614 TOPS2614 TOPS383 TOPs
FP6/FP4 MatrixTBD40 PFLOPs20 PFLOPsN/AN/AN/A
FP8 MatrixTBD20 PFLOPs5 PFLOPs2.6 PFLOPs2.6 PFLOPsN/A
FP16 MatrixTBD10 PFLOPs2.5 PFLOPs1.3 PFLOPs1.3 PFLOPs383 TFLOPs
FP32 VectorTBDTBD157.3 TFLOPs163.4 TFLOPs163.4 TFLOPs95.7 TFLOPs
FP64 VectorTBDTBD78.6 TFLOPs81.7 TFLOPs81.7 TFLOPs47.9 TFLOPs
VRAMTBD432 GB HBM4288 GB HBM3e256 GB HBM3e192 GB HBM3128 GB HBM2e
Infinity CacheTBDTBD256 MB256 MB256 MBN/A
Memory ClockTBD19.6 TB/s8.0 Gbps5.9 Gbps5.2 Gbps3.2 Gbps
Memory BusTBDTBD8192-bit8192-bit8192-bit8192-bit
Memory BandwidthTBDTBD8 TB/s6.0 TB/s5.3 TB/s3.2 TB/s
Form FactorTBDTBDOAMOAMOAMOAM
CoolingTBDTBDPassive / LiquidPassive CoolingPassive CoolingPassive Cooling
TDP (Max)TBDTBD1400W (355X)1000W750W560W

Follow Wccftech on Google to get more of our news coverage in your feeds.